Who plays Karen mother? What actor takes on the role of Karen Wheeler in the series? Who is the performer behind Karen Wheeler? Mrs. Wheeler is depicted by who? Which actor acts as the character of Karen the mother on the show? Who is the talent showcasing Karen Wheeler's character to life? What actor takes on the role of Karen Wheeler in the series? Whoever takes on the part of Karen Mrs. Wheeler? Whom is the talented individual enacting Karen Wheeler on the show? Which actor embodies the character of Karen Wheeler to the screen?