Who portrays Mrs. Wheeler mother? What actor embodies the role of Karen Wheeler in the show? Who is the performer behind Karen Wheeler? Mrs. Wheeler is brought to life by who? What actress plays the character of Karen Wheeler on the series? Who is the talent bringing Karen the mother's character to life? Which performer takes on the role of Karen Wheeler in the series? Who performs Karen Mrs. Wheeler? Who is the talented individual enacting Karen Wheeler on the show? Which actor incarnates the character of Karen Mrs. Wheeler to the screen?