Whom portrays Karen mother? What actor takes on the role of Karen Wheeler in the show? Whom is the performer behind Karen Wheeler? Mrs. Wheeler is brought to life by who? What actress plays the character of Karen the mother on the show? Who is the talent bringing Karen Wheeler's character to life? What actress takes on the role of Karen Mrs. Wheeler in the television show? Whoever takes on the part of Karen Mrs. Wheeler? Who is the talented individual portraying Karen Wheeler on the show? What actress brings the character of Karen Wheeler to the screen?